De novo seq. & analysis is a method used for the analysis of genome sequence of species with no reference genome. Genome sequence assembly is carried out using the DNA reads generated from the next-generation sequencing technology which is followed by consequent analysis on genetic information. Gene, repeated sequence and other genomic information are identified through various statistics as well as data mining model of completed base sequence.
Resequencing & analysis can be used to detect genetic difference based on known reference genome. It confirms the genetic information of a target species by aligning DNA reads generated from NGS technology to the reference genome. SNP, InDel, CNV and etc can be analysed using this method.
Exome seq. & analysis is used to sequence DNA from gene using NGS technology. Since the proportion of exon Is only 1~2% in whole genome, exome sequencing is a cheaper option to effectively analyze variant information compared to the whole genome sequencing.