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Metagenome Analysis

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Metagenome community analysis

Overview

Microbial communities show intra- or inter-species interaction in various environmental conditions. Hence research on microbial that are unable to be cultivated and macroscopic research such as the colony-level research are required for gaining deeper insights into microbial and developing its possible application. Metagenome community analysis does not require cultivation of microbial, it instead use DNA extracted from environmental sample. Also, it can improve our understanding on microbial through obtaining more genetic information via NGS technology followed by community analysis and serve as a mean to effectively use gene resources.

Workflow

Characteristics

STRENGTH
Analysis of microbial which cannot be cultivated
Acquisition of new biological information
Community analysis within a colony
OPPORTUNITY
Analysis of microbial colony, separation of gene and investigation on the function of the gene
Viral community analysis within the sample
Analysis of microbial colonies in human intestine
Classification of new microbial, Archaebacterium and etc

Metagenome assembly

Overview

Metagenome assembly is an analysis on population or isolate within the non-cultivated microbial community which use whole genome sequencing, de novo assembly and etc to analyze genetic information. This improves out understanding on microbial and provide us with the mean to effectively use gene resources.

Workflow

Characteristics

STRENGTH
Analysis of microbial which cannot be cultivated
Do not require reference genome
Enable acquisition of gene resources
OPPORTUNITY
Analysis of microbial colony associated with diseases, separation of gene and investigation on the function of the gene
Genetic disease prediction and diagnosis
Analysis of genome specific in the microbial colony
Classification of new microbial, Archaebacterium and etc
Identification of useful gene

Metatranscriptome analysis

Overview

Metagenome analysis is an analysis of gene expressed within the colony sample and the changed expression after certain treatment. It can be effectively used for identification of useful gene from various environments, cure for diseases and improvement of ecological system through understanding the mechanism for transcript regulation and regulation network. This will also improve our understanding on microbial and provide us with the mean to effectively use gene resources.

Workflow

Characteristics

STRENGTH
Analysis of microbial which cannot be cultivated
Acquisition of useful gene
Improvement in ecological system and treatment for diseases
OPPORTUNITY
Research on gene expression within microbial community through understanding the mechanism for transcript regulation
Analysis of the transcript regulation network to obtain genes associated with productivity and disease-resistance from agricultural microbial
Improvement of environment as well as the ecosystem through research on transcript regulation mechanism of microbial within the environment

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