본문 바로가기 주메뉴 바로가기

연구실적

HOME  >  주요성과  >  연구실적

Identifying candidate positive selection genes in Korean imported pig breeds

Genomics
Animal | Pig
Genes & Genomics | 08 May 2017
Domestication and artificial selection have modified the genome landscape of the pig. The identification of selection signatures in the genome can help to elucidate the selection mechanisms and uncover the causal genes related to the phenotypic variations between domestic pig breeds. We scanned the genomes of Korean imported pig breeds against native breeds using Z-transformed Fst (ZFST) and Heterozygosity (ZHp) statistics to search for the signatures of positive selection. We identified 411 (ZFST?=?175; ZHp?=?256) putatively selected genes in commercial breeds. The gene regions identified were harboring those related to immunity, coat color, reproduction function and other traits. Several genes (e.g., PLSCR4, AGTR1 and CORIN) were related to reproduction traits such as fertility, ovulation rate, and uterine function. This study revealed genes which improve our understanding of the biological mechanisms of higher litter sizes, the phenotype of interest, in higher litter pig breeds.

TOP